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It is bound to happen and naturally happens with any drug. Some prescribing physicians have reportedly been surprised at a previously hidden epidemic of narcolepsy among hard-working young professionals attending their surgeries. This reduces local GABAergic transmission, thereby diminishing GABA(A) receptor signalling on the mesolimbic dopamine terminals. But if you buy Provigil, this problem is sure to ward off. Get facts about the types of drug interactions, what substances or other things that may interact with drugs such as OTC drug and prescription drugs, vitamins, food(s) (grapefruit), and laboratory tests. Medication can be prescribed to treat sleepiness and episodes. Be careful if you drive or do anything that requires you to be alert. There is no definitive treatment for Kleine-Levin syndrome. 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