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CBMR researchers found one of the mechanisms that drives protein fibrillation

Several neurodegenerative diseases such as Alzheimer’s and prion diseases result from protein misfolding leading to the accumulation of protein aggregates shaped as amyloid fibrils. Using as model a simple protein we confirmed one of the mechanisms that drives protein fibrillation and more importantly we have elucidated how a simple sugar such as sucrose can delay protein fibrillation by compacting the globular structure of the protein.

Read the paper here.

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