CBMR researcher won Astrazeneca Innovate Competition Award

Ana Fernandes, CBMR researcher, won recently the Astrazeneca Innovate Competition Award, a prize of 3.000 euros, dedicated to support undergraduate college or master’s degree students involved in scientific research projects.

The prize, attributed during the iMed 9.0 Conference, which took place from 25th to 29th October, in Lisbon, aims to distinguish the work of Ana Fernandes in the field of breast cancer. In the talk “miRNA-mediated cis-regulation in breast cancer susceptibility” the researcher presented the results of her master’s thesis, developed under the supervision of Ana Teresa Maia and Joana Xavier, researchers at the Functional Genomics of Cancer Laboratory.

Gil Carraco

CBMR researcher receives Fulbright Grant to study embryonic development

Gil Carraco, CBMR researcher, won a Fulbright Grant for research with the PhD project “Regulating the pace of the Embryo Clock: RNA molecules in temporal control of vertebrate development”.
The main goal of the project is to perform direct mutagenesis using CRISP-Cas technology in zebrafish. The researcher seeks, during the nine-month research period at Harvard University, refine the embryonic clock model intra and inter-species.
The Portuguese researcher will work directly with Professor Alexander Schier, at the Department of Molecular and Cellular Biology (Harvard University).

For more information: http://cbmr.ualg.pt/research/stemcelldevelop/temporal-control-laboratory/


Clévio Nóbrega is the youngest and most promising European scientist

Clévio Nóbrega, CBMR researcher, has been awarded by European Society for Neurochemistry with the prize “Young Scientist Lecturship Award 2017”. The distinction, attributed to the youngest and most promising European scientist, aims to recognize the excellence of research developed in the field of neurochemistry.

This year, the award came to the Algarve, recognizing the merit and innovation of the projects of this researcher, Principal Investigator at the Centre for Biomedical Research and head of the Molecular Neuroscience and Gene Therapy Laboratory.

The prize will be delivered on August 22, in Paris, at the Annual Congress of International Society for Neurochemistry, where the researcher will give a conference on his projects.

We proudly announce that the young European scientist of the year is Portuguese, teaches at the Department of Biomedical Sciences and Medicine, at the University of Algarve, and develops research at the Centre for Biomedical Research. Congratulations, Clévio!


Bibiana Ferreira won a Terry Fox Grant

Bibiana Ferreira, CBMR researcher, won recently a Terry Fox Grant with the project “Characterizing the clinical relevance and the mechanism underlying TRIB2-mediated drug resistance to MEK inhibitiors in the context of melanoma”.
The project has been selected for funding by Liga Portuguesa Conta o Cancro.
The Terry Fox Program provides support to researchers conducting independent high-quality investigations in a complex area of cancer research. The purpose is to stimulate group interaction based on the premise that high impact work in complex areas of cancer research requires collaboration. The Terry Fox prize is designed for researchers with complementary skills, who investigate different aspects of a given cancer relevant topic, the results of which will be realized more rapidly and efficiently than if the individual projects were to be funded as a series of independent operating grants.

CBMR is distinguished with this prize for the fourth time, having been awarded, in previous years, the research projects of Wolfgang Link, Nuno Rodrigues dos Santos and Ana Luísa Martins Ferreira.

Congratulations, Bibiana! CBMR wish you the greatest success in this new project!


Bibiana Ferreira won Marie Curie European Reintegration Grant

Bibiana Ferreira, CBMR researcher, won recently a Marie Curie European Reintegration Grant with the project “Tribbles”. These individual grants assist the researchers from the EU and Associated States to become professionally reintegrated usually within their country of origin. It is intended that these grants will encourage researchers to include transnational mobility within the framework of their longer-term career.

Congratulations, Bibiana! CBMR wish you the greatest success in this new project!


CBMR is now part of the “Portuguese Roadmap of Research Infra-Structures”

CBMR won recently two projects on the behalf of the call “Portuguese Roadmap of Research Infra-Structures”, promoted by FCT (Fundação para a Ciência e Tecnologia). With this call aims to support research infrastructures (RI) of strategic interest, to underpin scientific and technological advances and bolster the capacity of the R&D community in Portugal to be an active member of European and international projects. The term “research infrastructure” refers to facilities, resources and related services that scientific communities use to develop cutting-edge research and innovation in specific fields, from social sciences to engineering and life sciences.

From CBMR the selected projects were: Genome Portugal National Facility for Genome Sequencing and Analysis, a consortium between Universidade de Aveiro, Universidade de Coimbra, Universidade do Porto, Universidade do Minho, Instituto Gulbenkian, Universidade de Lisboa, Instituto Nacional Dr.Ricardo Jorge e Universidade do Algarve and Portuguese Platform of Bioimaging (PPBI), a consortium between Universidade do Porto, Universidade do Minho, Universidade da Beira Interior, Universidade de Lisboa, Instituto Gulbenkian de Ciência, Fundação D.Anna Champalimaud e Fundação Dr.Carlos Champalimaud, and Universidade do Algarve, among other national research institutes.

Know more about the projects:

Genome Portugal – National Facility for Genome Sequencing and Analysis

GenomePortugal is a distributed genome sequencing and analysis RI for basic/applied genome research and advanced services, which aims to potentiate the participation of Portuguese scientists in national and international genome projects, and to promote genome research in important fields such as healthcare, drug discovery, environment, marine and freshwater resources, agrofood biotechnology and green chemistry. GenomePortugal congregates researchers and technical personnel from several national research centres, will put Portugal on the map of the countries with technological capacity and expertise to sequence and analyse complex genomes and will engage the Portuguese research community in the genome revolution.

CBMR/UAlg Principal Investigator: Ana Teresa-Maia

Portuguese Platform of Bioimaging (PPBI)

PPBI will boost collaboration between researchers, institutions and industry to strengthen both basic and applied research, matching high-impact R&D projects with state-of-art bioimaging resources and expertise. Through shared coordination, strategic investments, and efficient allocation of resources, PPBI wants to give national researchers access to cutting-edge technological resources, create conditions to attract international researchers and integrate Portugal in the international BioImaging roadmap.

CBMR/UAlg Principal Investigator: Cláudia Florindo



Liga Portuguesa contra o Cancro attributes research grant to Vânia Roberto

Vânia Roberto, CBMR Researcher, won a grant from Liga Portuguesa contra o Cancro to develop a post-doc project on the area of colon cancer. The project will be developed in the Epigenetics and Human Disease Laboratory on CBMR, and supervised by Prof. Pedro Castelo-Branco. We congratulate our researcher and wish her the greatest success.


Karl Magnus-Petersson is one of the 2016 Highly Cited Researchers

Karl Magnus-Petersson, researcher and coordinator of CBMR, was named by Thomson Reuters as one of the most cited researchers in the year of 2016. The research work of Karl Magnus-Petterson has been identified as being among the most valuable and significant in the field. Very few researchers earn this distinction – writing the greatest number of reports, officially designated by Essential Science Indicators as Highly Cited Papers. In addition, these reports rank among the top 1% most cited works for their subject field and year of publication, earning them the mark of exceptional impact.

We applaud the contribution of our researcher to the advancement of scientific discovery and innovation and wish him continued success!


Clévio Nobrega awarded with annual prize of Portuguese Society of Human Genetics

Clévio Nóbrega, CBMR researcher working in the field of neuroscience, particularly in the application of gene therapy to neurodegenerative diseases, is the latest winner of the annual prize of Portuguese Society of Human Genetics. The prize aims to distinguish the best international scientific article published in the field of genetics by a portuguese researcher.

This year the distinction was attributed to the CBMR researcher by the publication of the article “Reestablishing Ataxin -2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease”, a paper published last year in the renowned journal Brain.

The article, editor’s choice in 2016,  proposes to investigate the role and relevance of the protein ‘ataxin-2’ in Machado-Joseph disease (DMJ), a heritable disease characterized by “motor incoordination and muscular atrophy that provokes difficulties in swallowing, speech and vision”.

In this scientific article Clévio Nóbrega and his colleagues suggest that in Machado-Joseph disease, mutant ataxin-3 drives an abnormal reduction of ataxin-2 levels, which overactivates poly(A)-binding protein, increases translation of mutant ataxin-3 and other proteins and aggravates Machado-Joseph disease. Re-establishment of ataxin-2 levels reduces mutant ataxin-3 and alleviates Machado-Joseph disease pathogenesis opening a new avenue for therapeutic intervention in this and potentially other polyQ disorders.

See more here.